SCHEMBL9655232

SCHEMBL9655232

O=C(O)c1cccnc1C(=O)n1ccc2ccccc21

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
RAB9A P51151 1/20 0.55
ALDH1A1 P00352 3/20 0.53
KDM4E B2RXH2 2/20 0.53
CYP3A4 P08684 1/20 0.53
MAPT P10636 1/20 0.53
ALOX15 P16050 1/20 0.53
BLM P54132 1/20 0.53
AGER Q15109 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
NOTUM Q6P988 1/20 0.46
MET P08581 1/20 0.44
LMNA P02545 2/20 0.43
ALOX12 P18054 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
PARP1 P09874 1/20 0.42
MYC P01106 1/20 0.41
SLC22A12 Q96S37 1/20 0.41
NAPRT Q6XQN6 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9654115 0.82 L3MBTL1 (0.69) TSHRL3MBTL1RAB9AALDH1A1ALOX15
SCHEMBL9655173 0.75 L3MBTL1 (0.59) TSHRL3MBTL1RAB9AALDH1A1MAPT
SCHEMBL28395173 0.75 L3MBTL1 (0.58) TSHRL3MBTL1RAB9AALDH1A1KDM4E
SCHEMBL31435512 0.72 RAB9A (1.00) TSHRL3MBTL1RAB9AALDH1A1KDM4E
SCHEMBL1413391 0.72 RAB9A (1.00) TSHRL3MBTL1RAB9AALDH1A1KDM4E
Quinolinic Acid SCHEMBL343618 0.71 KDM4E (1.00) TSHRL3MBTL1ALDH1A1KDM4ECYP3A4
Quinolinic Acid SCHEMBL69230 0.71 KDM4E (1.00) TSHRL3MBTL1ALDH1A1KDM4ECYP3A4
Quinolinic Acid SCHEMBL27676801 0.71 KDM4E (1.00) TSHRL3MBTL1ALDH1A1KDM4ECYP3A4
Quinolinic Acid SCHEMBL29356188 0.71 KDM4E (1.00) TSHRL3MBTL1ALDH1A1KDM4ECYP3A4
SCHEMBL9263968 0.70 TSHR (0.75) TSHRL3MBTL1RAB9AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0262810-B1 SHEET RECORDING MATERIAL CONTAINING DYE-FORMING COMPONENTS Fuji Photo Film Co., Ltd. (JP) 1992-12-09 EP disclosed
US-4808566-A COLORLESS DYE IS DIMER OF 3-(4-SUBSTITUTED AMINOARYL)-3-(SUBSTITUTED INDOL-3-YL) PHTHALIDE FUJI PHOTO FILM CO., LTD. (JP) 1989-02-28 US disclosed
US-4800193-A ANILINE, INDOLE AND PHTHALEIN DYES; COLORFASTNESS; AROMATIC SOLVENT-SOLUBLE FUJI PHOTO FILM CO., LTD. (JP) 1989-01-24 US disclosed
EP-0262810-A2 Sheet recording material containing dye-forming components Fuji Photo Film Co., Ltd. (JP) 1988-04-06 EP disclosed