SCHEMBL9655173

SCHEMBL9655173

O=C(O)c1cccc(C(=O)n2ccc3ccccc32)c1C(=O)O

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.59
TSHR P16473 1/20 0.59
RAB9A P51151 1/20 0.59
NOTUM Q6P988 1/20 0.50
NR4A1 P22736 1/20 0.42
NR4A2 P43354 1/20 0.42
NR4A3 Q92570 1/20 0.42
CDC25B P30305 1/20 0.41
KMT2A Q03164 1/20 0.41
TFPI2 P48307 1/20 0.40
NPY4R P50391 1/20 0.40
ALDH1A1 P00352 2/20 0.38
ALOX15 P16050 1/20 0.38
DAO P14920 1/20 0.38
HSD17B10 Q99714 1/20 0.38
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
MCL1 Q07820 1/20 0.37
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9654115 0.89 L3MBTL1 (0.69) L3MBTL1TSHRRAB9ANOTUMNR4A1
SCHEMBL21777692 0.80 TSHR (0.60) L3MBTL1TSHRRAB9ANOTUMNR4A1
SCHEMBL28835530 0.76 TSHR (0.60) L3MBTL1TSHRRAB9ANOTUMKMT2A
SCHEMBL28921429 0.76 L3MBTL1 (0.60) L3MBTL1TSHRRAB9ANOTUMKMT2A
SCHEMBL28864285 0.76 TSHR (0.60) L3MBTL1TSHRRAB9ANOTUMKMT2A
SCHEMBL8447109 0.76 RAB9A (0.60) L3MBTL1TSHRRAB9ANOTUMKMT2A
SCHEMBL29494636 0.76 RAB9A (0.60) L3MBTL1TSHRRAB9ANOTUMKMT2A
SCHEMBL28529485 0.76 RAB9A (0.60) L3MBTL1TSHRRAB9ANOTUMKMT2A
SCHEMBL27541965 0.76 RAB9A (0.59) L3MBTL1TSHRRAB9ANOTUMKMT2A
SCHEMBL9655232 0.75 TSHR (0.55) L3MBTL1TSHRRAB9ANOTUMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0262810-B1 SHEET RECORDING MATERIAL CONTAINING DYE-FORMING COMPONENTS Fuji Photo Film Co., Ltd. (JP) 1992-12-09 EP disclosed
US-4808566-A COLORLESS DYE IS DIMER OF 3-(4-SUBSTITUTED AMINOARYL)-3-(SUBSTITUTED INDOL-3-YL) PHTHALIDE FUJI PHOTO FILM CO., LTD. (JP) 1989-02-28 US disclosed