Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655344 | 0.81 | ALDH1A1 (0.39) | KDM4EKDRRAB9AKMT2ANPC1 | |
| SCHEMBL7048087 | 0.71 | KDM4E (0.33) | KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8296199 | 0.70 | ERN1 (0.42) | KDM4EKMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL9655534 | 0.67 | GABRA1 (0.40) | KDM4EKMT2AMEN1 | |
| SCHEMBL7047960 | 0.66 | AKR1C4 (0.37) | KDM4EMAPTTSHRHSD17B10ALDH1A1 | |
| SCHEMBL9354205 | 0.65 | ALDH1A1 (0.42) | KDM4ERAB9AMAPTSMN1; SMN2TSHR | |
| SCHEMBL2763225 | 0.64 | ALDH1A1 (0.57) | KDM4EKMT2AMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL28839615 | 0.64 | TAS1R3 (0.57) | KDM4EKMT2ANPC1MAPTMEN1 | |
| SCHEMBL10807704 | 0.62 | SLC22A12 (0.37) | KDM4EKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL8411036 | 0.62 | KDM4E (0.46) | KDM4ERAB9AKMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496332-A1 | Alpha-aminoquinolinoyl-[3]-penicillines, process for their preparation and their use as antibacterial agents | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |