Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.49 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.49 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655466 | 0.86 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AMAPTHSPB1 | |
| SCHEMBL9655475 | 0.86 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AMAPTHSPB1 | |
| SCHEMBL27527530 | 0.85 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AMAPTHSPB1 | |
| SCHEMBL8616810 | 0.82 | HSPB1 (0.51) | ALDH1A1MEN1KMT2AMAPTHSPB1 | |
| SCHEMBL708511 | 0.81 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AMAPTHSPB1 | |
| SCHEMBL29390372 | 0.81 | HSPB1 (0.73) | ALDH1A1MEN1KMT2AMAPTHSPB1 | |
| SCHEMBL1042708 | 0.81 | HSPB1 (0.73) | ALDH1A1MEN1KMT2AMAPTHSPB1 | |
| SCHEMBL5148413 | 0.80 | ALPL (0.48) | ALDH1A1MEN1KMT2AMAPTHSPB1 | |
| SCHEMBL30062473 | 0.80 | ALPL (0.48) | ALDH1A1MEN1KMT2AMAPTHSPB1 | |
| SCHEMBL28774757 | 0.79 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AMAPTHSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105622757-A | Antibodies that bind to lysyl oxidase-like 2(LOXL2) and methods of use therefor | GILEAD BIOLOGICS INC | 2016-06-01 | — | — | CN | disclosed |
| CN-101230026-B | Method for preparing 4,4'-di(2,4-dinitro-phenoxy) sulfone | UNIV DONGHUA | 2012-07-18 | — | — | CN | disclosed |
| CN-101245041-B | Process for producing 4,4'-bis(2,4-diaminophenyloxy)diphenyl sulfone | UNIV DONGHUA | 2010-12-01 | — | — | CN | disclosed |
| CN-101245041-A | Process for producing 4,4'-bis(2,4-diaminophenyloxy)diphenyl sulfone | UNIV DONGHUA (CN) | 2008-08-20 | — | — | CN | disclosed |
| CN-101230026-A | Method for preparing 4,4'-di(2,4-dinitro-phenoxy) sulfone | UNIV DONGHUA (CN) | 2008-07-30 | — | — | CN | disclosed |
| EP-0226516-B1 | AMIDE DERIVATIVES AND ANTIALLERGIC AGENTS CONTAINING THE SAME | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4906631-A | Amide derivatives and antiallergic agents containing the same | TERUMO KABUSHIKI KAISHA (JP) | 1990-03-06 | — | — | US | disclosed |
| US-4859673-A | Amide derivatives and antiallergic agents containing the same | TERUMO KABUSHIKI KAISHA (JP) | 1989-08-22 | — | — | US | disclosed |
| US-4795752-A | Amide derivatives and antiallergic agents containing the same | TERUMO KABUSHIKI KAISHA (JP) | 1989-01-03 | — | — | US | disclosed |
| EP-0244319-A2 | Amide derivatives and antiallergic agents containing the same | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1987-11-04 | — | — | EP | disclosed |
| EP-0226516-A2 | Amide derivatives and antiallergic agents containing the same | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1987-06-24 | — | — | EP | disclosed |