SCHEMBL9655656

SCHEMBL9655656

CC(C)=C1CC(=O)N(c2cc(O)c(Cl)cc2Cl)C1=O

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
HSP90AA1 P07900 4/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
GAA P10253 2/20 0.33
MAPT P10636 1/20 0.33
ALOX12 P18054 1/20 0.33
PKM P14618 1/20 0.33
CASP6 P55212 1/20 0.33
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9655322 0.89 MEN1 (0.35) HPGDHSP90AA1MEN1KMT2AGAA
SCHEMBL9654778 0.81 PKM (0.46) HPGDTSHRHSP90AA1MEN1KMT2A
SCHEMBL9655371 0.79 ALDH1A1 (0.40) HPGDTSHRHSD17B10MEN1KMT2A
SCHEMBL9655637 0.78 PKM (0.41) HSP90AA1GAAMAPTPKM
SCHEMBL9654864 0.78 GAA (0.52) MEN1KMT2AGAAMAPTPKM
SCHEMBL9656292 0.77 GAA (0.38) HSP90AA1MEN1KMT2AGAAMAPT
SCHEMBL9655971 0.77 GAA (0.38) HSP90AA1MEN1KMT2AGAAMAPT
SCHEMBL9654784 0.76 PPOX (0.43) HPGDGAAPKM
SCHEMBL9652343 0.76 PPOX (0.50) GAAMAPTPKM
SCHEMBL9655608 0.76 GAA (0.45) GAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61183265-A None JP disclosed
EP-0190755-B1 AN N-SUBSTITUTED-PHENYLTERACONIMIDE COMPOUND, HERBICIDAL COMPOSITION, AND METHOD FOR THE DESTRUCTION OF UNDESIRABLE WEEDS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1992-06-17 EP disclosed
US-4964905-A N-substituted-phenylteraconimide compound, herbicidal composition, and method for the destruction of undesirable weeds ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1990-10-23 US disclosed
JP-S61183265-A NOVEL TERACONIC ACID IMIDE DERIVATIVE AND HERBICIDE CONTAINING SAME AS ACTIVE CONSTITUENT ASAHI CHEM IND CO LTD 1986-08-15 JP disclosed
EP-0190755-A2 An n-substituted-phenylteraconimide compound, herbicidal composition, and method for the destruction of undesirable weeds Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-08-13 EP disclosed