SCHEMBL564406

SCHEMBL564406

C/C(=N/NC(=O)c1ccncc1)c1ccco1

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.66
RAB9A P51151 6/20 0.64
GAA P10253 4/20 0.64
NPC1 O15118 4/20 0.64
SMN1; SMN2 Q16637 3/20 0.64
PKM P14618 2/20 0.64
KMT2A Q03164 4/20 0.62
MEN1 O00255 2/20 0.62
ALDH1A1 P00352 2/20 0.62
MAPT P10636 2/20 0.62
MCL1 Q07820 1/20 0.62
CTDSP1 Q9GZU7 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.60
CYP3A4 P08684 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29534219 1.00 POLB (0.66) POLBRAB9AGAANPC1SMN1; SMN2
SCHEMBL119577 1.00 POLB (0.66) POLBRAB9AGAANPC1SMN1; SMN2
SCHEMBL8292484 0.78 POLB (0.59) POLBRAB9AGAANPC1SMN1; SMN2
Isonicotinoylhydrazone Of Acetophenone SCHEMBL6637694 0.78 GAA (0.76) POLBRAB9AGAANPC1SMN1; SMN2
Isonicotinoylhydrazone Of Acetophenone SCHEMBL6637701 0.78 GAA (0.76) POLBRAB9AGAANPC1SMN1; SMN2
SCHEMBL9656226 0.77 POLB (0.69) POLBRAB9AGAANPC1SMN1; SMN2
SCHEMBL9656234 0.77 POLB (0.69) POLBRAB9AGAANPC1SMN1; SMN2
SCHEMBL14938452 0.76 POLB (0.68) POLBRAB9AGAANPC1SMN1; SMN2
SCHEMBL2997492 0.75 GAA (0.62) POLBRAB9AGAANPC1KMT2A
SCHEMBL11606677 0.75 RAB9A (0.74) POLBRAB9AGAANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022040799-A1 ANTIMICROBIAL COMPOSITION GP TECH INOVASYON TEKNOLOJI VE ARASTIRMA A.S (TR) 2022-03-03 WO claimed
CN-109788757-A Herbicidal mixtures 先正达参股股份有限公司 2019-05-21 CN claimed
CN-109788756-A Herbicidal mixtures 先正达参股股份有限公司 2019-05-21 CN claimed
CN-109561696-A The method for controlling plant 先正达参股股份有限公司 2019-04-02 CN claimed
CN-107529752-A Herbicidal mixture 先正达参股股份有限公司 2018-01-02 CN claimed
EP-2560634-A1 NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS Piramal Enterprises Limited (IN) 2013-02-27 EP claimed
WO-2011132171-A1 NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS PIRAMAL LIFE SCIENCES LIMITED (IN) 2011-10-27 WO claimed
US-20110263526-A1 Nitric Oxide Releasing Prodrugs of Therapeutic Agents PIRAMAL LIFE SCIENCES LIMITED (IN) 2011-10-27 US claimed
US-20090131342-A1 Nitrosated and/or nitrosylated compounds, compositions and methods of use NITROMED, INC. (US) 2009-05-21 US claimed
EP-1718286-A2 NITROSATED AND/OR NITROSYLATED COMPOUNDS, COMPOSITIONS AND METHODS OF USE Nitromed, Inc. (US) 2006-11-08 EP claimed
WO-2005070006-A2 NITROSATED AND/OR NITROSYLATED COMPOUNDS, COMPOSITIONS AND METHODS OF USE NITROMED, INC. (US) 2005-08-04 WO claimed
US-20030105066-A1 Nitrate salts of antimicrobial agents NICOX S.A. (FR) 2003-06-05 US claimed
CN-1419450-A Nitrate salts of antimicrobial drugs NICOX SA (FR) 2003-05-21 CN claimed
EP-1253924-A1 NITRATE SALTS OF ANTIMICROBIAL AGENTS NICOX S.A. (FR) 2002-11-06 EP claimed
WO-2001054691-A1 NITRATE SALTS OF ANTIMICROBIAL AGENTS NICOX, S.A. (FR) 2001-08-02 WO claimed
US-20260060822-A1 BIOENGINEERED SCAFFOLDS FOR VASCULAR GRAFTS AND METHODS OF USE THEREOF UNIV WAKE FOREST HEALTH SCIENCES (US) 2026-03-05 US disclosed
US-20260014091-A1 COMPOSITIONS AND METHODS OF MAKING AND USE THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2026-01-15 US disclosed
EP-0741570-A1 METHOD FOR PREVENTING OR REDUCING PHOTOSENSITIVITY AND/OR PHOTOTOXICITY REACTIONS TO MEDICATIONS G.D. SEARLE & CO. (US) 1996-11-13 EP disclosed
WO-1995020387-A1 METHOD FOR PREVENTING OR REDUCING PHOTOSENSITIVITY AND/OR PHOTOTOXICITY REACTIONS TO MEDICATIONS G.D. SEARLE & CO. (US) 1995-08-03 WO disclosed
US-4188382-A Thiazolinyl (thiazolyl) phosphonamidates and phosphoramidates pesticidal and herbicidal compositions based thereon Vsesojuzny Nauchno, et al. (SU) 1980-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014091-A1 COMPOSITIONS AND METHODS OF MAKING AND USE THEREOF ERBB3, ERBB2, EGFR POLB 4642/4885RAB9A 1599/4885GAA 3713/4885
US-20090131342-A1 Nitrosated and/or nitrosylated compounds, compositions and methods of use LTC4S, LTB4R2, LTB4R POLB 1382/4885RAB9A 3511/4885GAA 1173/4885
US-20260060822-A1 BIOENGINEERED SCAFFOLDS FOR VASCULAR GRAFTS AND METHODS OF USE THEREOF PFKP, PBK, MYLK POLB 3602/4885RAB9A 4527/4885GAA 562/4885
US-20110263526-A1 Nitric Oxide Releasing Prodrugs of Therapeutic Agents NOS2, NOS1, NOS3 POLB 3686/4885RAB9A 3125/4885GAA 1775/4885
US-20030105066-A1 Nitrate salts of antimicrobial agents NOS1, NOS3, NOS2 POLB 575/4885RAB9A 4032/4885GAA 392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.