Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657975 | 0.98 | ALOX5 (0.54) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9657122 | 0.87 | KDM4E (0.47) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9627705 | 0.86 | KDM4E (0.46) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9629454 | 0.86 | KDM4E (0.49) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9658484 | 0.85 | ALOX5 (0.55) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9627757 | 0.84 | ALOX5 (0.46) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9627928 | 0.84 | KDM4E (0.47) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9444174 | 0.82 | KDM4E (0.59) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30945149 | 0.82 | KDM4E (0.59) | ALOX5KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11880150 | 0.80 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |