Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | LDHB | P07195 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657719 | 0.90 | LDHA (0.49) | ALOX5LDHALDHBKDM4EALDH1A1 | |
| SCHEMBL9656389 | 0.85 | ALOX5 (0.56) | ALOX5PTGS2KDM4EALDH1A1HPGD | |
| SCHEMBL9657975 | 0.84 | ALOX5 (0.54) | ALOX5PTGS2KDM4EALDH1A1HPGD | |
| SCHEMBL9654924 | 0.74 | ABCB11 (0.42) | ALOX5LDHALDHBKDM4EALDH1A1 | |
| SCHEMBL9657723 | 0.74 | ALOX5 (0.38) | ALOX5PTGS2LDHALDHBKDM4E | |
| SCHEMBL9657954 | 0.74 | ABCB11 (0.42) | ALOX5LDHALDHBKDM4EALDH1A1 | |
| SCHEMBL9629355 | 0.74 | LDHA (0.48) | ALOX5LDHALDHBKDM4EALDH1A1 | |
| SCHEMBL9657958 | 0.74 | LDHA (0.48) | ALOX5LDHALDHBKDM4EALDH1A1 | |
| SCHEMBL9656656 | 0.74 | LDHA (0.41) | LDHALDHBKDM4EALDH1A1HPGD | |
| SCHEMBL9627724 | 0.73 | ALOX5 (0.48) | ALOX5PTGS2LDHALDHBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |