Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736815 | 0.90 | NOTUM (0.56) | ALOX5NOTUM | |
| SCHEMBL9736607 | 0.68 | NOTUM (0.39) | NOTUM | |
| SCHEMBL9656449 | 0.68 | ALOX5 (0.37) | ALOX5 | |
| SCHEMBL30684094 | 0.67 | CYP1A2 (0.40) | NOTUM | |
| SCHEMBL28330578 | 0.65 | PLA2G10 (0.47) | — | |
| SCHEMBL18229909 | 0.65 | NOTUM (0.46) | NOTUM | |
| SCHEMBL6168100 | 0.64 | PLA2G10 (0.40) | — | |
| SCHEMBL21028082 | 0.63 | NR1H2 (0.35) | NOTUM | |
| SCHEMBL19067224 | 0.63 | HTR2A (0.42) | NOTUM | |
| SCHEMBL21028020 | 0.63 | HTR2A (0.38) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021678-A1 | LIPOXYGENASE INHIBITING PYRROLO [1,2a]INDOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-12-10 | — | — | WO | disclosed |
| US-5128364-A | Antiasthmatic, antiallergic, antiinflammatory and cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1992-07-07 | — | — | US | disclosed |