Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21028079 | 0.77 | NR1H2 (0.37) | NOTUMOGFRL1SIGMAR1OPRM1OPRD1 | |
| SCHEMBL18229909 | 0.72 | NOTUM (0.46) | NOTUMALDH1A1DAOTSHRMCL1 | |
| SCHEMBL21028020 | 0.71 | HTR2A (0.38) | NOTUMMEN1KMT2ACNR2SIGMAR1 | |
| SCHEMBL21028027 | 0.69 | KMT2A (0.37) | CYP1A2NOTUMALDH1A1SMN1; SMN2MEN1 | |
| Acetic Acid SCHEMBL13279290 | 0.68 | HTR2A (0.55) | SIGMAR1 | |
| SCHEMBL9816566 | 0.68 | ALDH1A1 (0.54) | OGFRL1ALDH1A1DAOTSHRMCL1 | |
| SCHEMBL9736607 | 0.67 | NOTUM (0.39) | CYP1A2NOTUMALDH1A1SMN1; SMN2DAO | |
| SCHEMBL9656458 | 0.67 | ALOX5 (0.40) | NOTUM | |
| SCHEMBL8447696 | 0.67 | HTR2A (0.43) | NOTUMDAOSIGMAR1 | |
| SCHEMBL7901361 | 0.66 | DAO (0.47) | CYP1A2ALDH1A1DAOMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235809-A1 | CGAS INHIBITORS | ELI LILLY AND COMPANY (US) | 2023-12-07 | — | — | WO | disclosed |