Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656428 | 0.81 | CSNK2A2 (0.43) | ESR1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9654846 | 0.81 | CSNK2A2 (0.43) | ESR1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9657666 | 0.79 | EP300 (0.43) | ALDH1A1KMT2AKDM4ECYP3A4MAPT | |
| SCHEMBL29700360 | 0.78 | LMNA (0.50) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL9657859 | 0.78 | LMNA (0.50) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL9657182 | 0.76 | TSHR (0.44) | ALDH1A1MEN1KMT2ATSHRMAPT | |
| SCHEMBL9657787 | 0.76 | HPGD (0.44) | ESR1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9656717 | 0.76 | PPM1A (0.40) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL9656398 | 0.74 | MAPT (0.46) | ALDH1A1MEN1KMT2ATSHRMAPT | |
| SCHEMBL9658438 | 0.73 | ADORA1 (0.43) | ALDH1A1MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |