Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.56 |
| ▸ | FAAH | O00519 | 2/20 | 0.53 |
| ▸ | LHCGR | P22888 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656686 | 0.85 | RAB9A (0.56) | ALDH1A1RAB9AEPHX1FAAH | |
| SCHEMBL9658220 | 0.84 | EPHX1 (0.55) | ALDH1A1RAB9AEPHX1FAAH | |
| SCHEMBL9657649 | 0.84 | ABCB11 (0.58) | ALDH1A1RAB9AEPHX1FAAH | |
| SCHEMBL9657915 | 0.83 | ALDH1A1 (0.69) | ALDH1A1RAB9AEPHX1FAAHLHCGR | |
| SCHEMBL9657148 | 0.83 | ALDH1A1 (0.53) | ALDH1A1RAB9AEPHX1FAAHLHCGR | |
| SCHEMBL17509959 | 0.81 | EPHX1 (0.67) | ALDH1A1RAB9AEPHX1FAAHLHCGR | |
| SCHEMBL9656760 | 0.78 | ESR1 (0.51) | ALDH1A1RAB9A | |
| SCHEMBL15094119 | 0.78 | EPHX1 (0.61) | ALDH1A1RAB9AEPHX1FAAH | |
| SCHEMBL9657202 | 0.76 | EPHX1 (0.55) | ALDH1A1RAB9AEPHX1FAAH | |
| SCHEMBL15085012 | 0.76 | EPHX1 (0.60) | ALDH1A1RAB9AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |