Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.55 |
| ▸ | MGLL | Q99685 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656357 | 0.94 | MGLL (0.54) | NCEH1MGLLHTT | |
| SCHEMBL9656406 | 0.91 | KDM4E (0.46) | NCEH1 | |
| SCHEMBL9658423 | 0.87 | NCEH1 (0.54) | NCEH1MGLLTSHRHTT | |
| SCHEMBL9658242 | 0.86 | NCEH1 (0.53) | NCEH1MGLLTSHRHTT | |
| SCHEMBL9660367 | 0.85 | NCEH1 (0.53) | NCEH1MGLL | |
| SCHEMBL9656418 | 0.85 | NCEH1 (0.52) | NCEH1MGLL | |
| SCHEMBL9657711 | 0.84 | KDM4E (0.49) | NCEH1 | |
| SCHEMBL9657637 | 0.84 | NCEH1 (0.55) | NCEH1MGLL | |
| SCHEMBL9659913 | 0.84 | NCEH1 (0.55) | NCEH1MGLL | |
| SCHEMBL9656416 | 0.84 | ABCB11 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |