Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 10/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9658195 | 0.89 | POLB (0.56) | CASP6TSHRPOLBLMNAMEN1 | |
| SCHEMBL10955118 | 0.81 | GSTP1 (0.44) | MEN1KMT2A | |
| SCHEMBL7591997 | 0.80 | CASP6 (0.64) | CASP6TSHRPOLBLMNAMEN1 | |
| SCHEMBL31401277 | 0.79 | PTK2B (0.52) | POLBLMNAMEN1KMT2A | |
| SCHEMBL18113472 | 0.79 | CASP6 (0.62) | CASP6TSHRPOLBLMNAMEN1 | |
| SCHEMBL9500729 | 0.77 | CASP6 (0.58) | CASP6TSHRPOLBLMNAMEN1 | |
| SCHEMBL31401069 | 0.76 | SMN1; SMN2 (0.52) | TSHRPOLBKMT2AAPEX1 | |
| SCHEMBL27506959 | 0.76 | TSHR (0.47) | CASP6TSHRPOLBLMNAMEN1 | |
| SCHEMBL23704932 | 0.75 | CASP6 (0.57) | CASP6TSHRPOLBLMNAMEN1 | |
| SCHEMBL9658492 | 0.75 | DTYMK (0.51) | CASP6TSHRPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5101069-A | PROCESS FOR THE PREPARATION OF HYDROXYETHYLSULFONYLNITRO- AND HYDROXYETHYLSULFONYLAMINO-BENZOIC ACIDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |
| US-4960929-A | Chemical intermediate for making fiber reactive azo dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |