Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HCAR3 | P49019 | 10/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499862 | 0.88 | POLB (0.59) | CASP6TSHRHCAR3POLBLMNA | |
| SCHEMBL18113472 | 0.84 | CASP6 (0.62) | CASP6TSHRHCAR3POLBLMNA | |
| SCHEMBL7591997 | 0.83 | CASP6 (0.64) | CASP6TSHRHCAR3POLBLMNA | |
| SCHEMBL23704932 | 0.81 | CASP6 (0.57) | CASP6TSHRHCAR3POLBLMNA | |
| SCHEMBL9657284 | 0.79 | CASP6 (0.55) | CASP6TSHRHCAR3POLBLMNA | |
| SCHEMBL9657287 | 0.77 | CASP6 (0.55) | CASP6TSHRHCAR3POLBLMNA | |
| SCHEMBL20150216 | 0.75 | VCAM1 (0.55) | CASP6TSHRPOLBMEN1KMT2A | |
| SCHEMBL3530451 | 0.75 | VCAM1 (0.71) | CASP6TSHRHCAR3POLBLMNA | |
| SCHEMBL504055 | 0.75 | CASP6 (1.00) | CASP6TSHRHCAR3LMNA | |
| SCHEMBL29577830 | 0.75 | CASP6 (1.00) | CASP6TSHRHCAR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312922-B1 | OXETHYLSULFONYL-NITRO- OR -AMINO-BENZOIC ACIDS AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-02 | — | — | EP | disclosed |
| EP-0312922-A2 | Oxethylsulfonyl-nitro- or -amino-benzoic acids and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-26 | — | — | EP | disclosed |