SCHEMBL7591997

SCHEMBL7591997

O=C(O)c1ccc([N+](=O)[O-])c(S(=O)(=O)O)c1

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 1/20 0.64
TSHR P16473 2/20 0.58
LMNA P02545 1/20 0.54
POLB P06746 2/20 0.52
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
HCAR3 P49019 8/20 0.50
APEX1 P27695 1/20 0.47
TDP1 Q9NUW8 1/20 0.46
ALKBH2 Q6NS38 1/20 0.45
ALKBH5 Q6P6C2 1/20 0.45
ALKBH3 Q96Q83 1/20 0.45
FTO Q9C0B1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9185447 0.87 CASP6 (0.64) CASP6TSHRLMNAPOLBMEN1
SCHEMBL18113472 0.85 CASP6 (0.62) CASP6TSHRLMNAPOLBMEN1
SCHEMBL28909765 0.85 POLB (0.62) CASP6TSHRLMNAPOLBMEN1
SCHEMBL9500729 0.83 CASP6 (0.58) CASP6TSHRLMNAPOLBMEN1
SCHEMBL23704932 0.81 CASP6 (0.57) CASP6TSHRLMNAPOLBMEN1
SCHEMBL9657287 0.80 CASP6 (0.55) CASP6TSHRLMNAPOLBMEN1
SCHEMBL9657284 0.80 CASP6 (0.55) CASP6TSHRLMNAPOLBMEN1
SCHEMBL29535309 0.79 ALDH1A1 (0.54) CASP6LMNAMEN1KMT2ATDP1
SCHEMBL9163223 0.79 ALDH1A1 (0.54) CASP6LMNAMEN1KMT2ATDP1
SCHEMBL29577830 0.78 CASP6 (1.00) CASP6TSHRLMNAHCAR3APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0897910-B1 Process for the preparation of 2-carboxy-5-nitrobenzene sulphonic acid and its salts by oxidation BAYER CROPSCIENCE GMBH (DE) 2002-11-06 EP disclosed
EP-0897910-A1 Process for the preparation of 2-carboxy-5-nitrobenzene sulphonic acid and its salts by oxidation Hoechst Schering AgrEvo GmbH (DE) 1999-02-24 EP disclosed