Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10643955 | 0.89 | ABCB11 (0.44) | — | |
| SCHEMBL9654842 | 0.85 | ABCB11 (0.47) | POLBTHRBRECQLTDP1L3MBTL1 | |
| SCHEMBL9656605 | 0.85 | NCEH1 (0.44) | POLB | |
| SCHEMBL9657721 | 0.83 | MGLL (0.47) | — | |
| SCHEMBL9660646 | 0.82 | SLC2A1 (0.45) | POLB | |
| SCHEMBL9657769 | 0.81 | MGLL (0.54) | — | |
| SCHEMBL9658010 | 0.81 | SLC2A1 (0.48) | — | |
| SCHEMBL9628176 | 0.80 | ABCB11 (0.56) | POLB | |
| SCHEMBL9660000 | 0.80 | ABCB11 (0.44) | POLB | |
| SCHEMBL9657945 | 0.80 | ABCB11 (0.47) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |