Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.52 |
| ▸ | MMP13 | P45452 | 7/20 | 0.52 |
| ▸ | MMP8 | P22894 | 6/20 | 0.52 |
| ▸ | MMP12 | P39900 | 6/20 | 0.52 |
| ▸ | MMP14 | P50281 | 6/20 | 0.52 |
| ▸ | MMP16 | P51512 | 6/20 | 0.52 |
| ▸ | MMP9 | P14780 | 5/20 | 0.52 |
| ▸ | MMP3 | P08254 | 4/20 | 0.46 |
| ▸ | MMP1 | P03956 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | BAX | Q07812 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9661649 | 0.91 | MMP2 (0.52) | MMP2MMP13MMP8MMP12MMP14 | |
| SCHEMBL9660874 | 0.82 | LTA4H (0.47) | MMP2MMP13MMP8MMP12MMP14 | |
| SCHEMBL9659641 | 0.79 | MMP2 (0.53) | MMP2MMP13MMP8MMP12MMP14 | |
| SCHEMBL9661773 | 0.77 | LTA4H (0.49) | MMP2MMP13MMP8MMP12MMP14 | |
| SCHEMBL23430824 | 0.77 | LTA4H (0.69) | MMP2MMP13MMP8MMP12MMP14 | |
| SCHEMBL416827 | 0.77 | LTA4H (0.69) | MMP2MMP13MMP8MMP12MMP14 | |
| SCHEMBL9661560 | 0.75 | PKM (0.61) | MMP2MMP13MMP8MMP12MMP14 | |
| SCHEMBL9662395 | 0.75 | GAA (0.54) | MMP2MMP13MMP8MMP12MMP14 | |
| SCHEMBL2412893 | 0.74 | LTA4H (0.47) | LTA4HNR1H2BAXPPARGPPARD | |
| SCHEMBL5209521 | 0.74 | LTA4H (0.50) | HTTLTA4HNR1H2BAXTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466096-A1 | Derivatives of 4-hydroxyphenylsulfone | JUJO PAPER CO., LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |