Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | MMP12 | P39900 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9661612 | 0.88 | CA2 (0.46) | CA1CA2CA7CA9CA12 | |
| SCHEMBL9662382 | 0.84 | PDIA6 (0.50) | LTA4HCA1CA2CA7CA9 | |
| SCHEMBL9659646 | 0.82 | MMP2 (0.52) | LTA4HGAAPKML3MBTL1ELANE | |
| SCHEMBL51603 | 0.80 | LTA4H (0.66) | LTA4HCA1CA2CA7CA9 | |
| SCHEMBL9659651 | 0.79 | CA12 (0.50) | LTA4HCA1CA2CA7CA9 | |
| SCHEMBL9659663 | 0.79 | PPARG (0.39) | LTA4HCA1CA2CA7CA9 | |
| SCHEMBL9661813 | 0.77 | CA12 (0.51) | LTA4HCA1CA2CA7CA9 | |
| SCHEMBL9661638 | 0.77 | MEN1 (0.42) | CA1CA2CA7CA9CA12 | |
| SCHEMBL9661560 | 0.77 | PKM (0.61) | CA1CA2GAAPKMELANE | |
| SCHEMBL9660869 | 0.76 | CA2 (0.54) | LTA4HCA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466096-A1 | Derivatives of 4-hydroxyphenylsulfone | JUJO PAPER CO., LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |