SCHEMBL9660490

SCHEMBL9660490

CCCCc1ccc(Cc2c3ccccc3cc3ccccc23)cc1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 4/20 0.43
TLR8 Q9NR97 4/20 0.43
DHODH Q02127 1/20 0.43
HTR2A P28223 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CTSV O60911 1/20 0.43
CTSL P07711 1/20 0.43
BCHE P06276 1/20 0.41
CNR2 P34972 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7915017 0.82 HTR2A (0.52) TLR8HTR2AL3MBTL1MAPT
SCHEMBL17423277 0.82 KDM4E (0.59) PTPN1TLR8DHODH
SCHEMBL8866398 0.79 CYP1A2 (0.48) HTR2AL3MBTL1
SCHEMBL4642432 0.78 HTR2A (0.56) HTR2AL3MBTL1
SCHEMBL299862 0.77 MAPT (0.53) TLR8HTR2AL3MBTL1MAPT
SCHEMBL29104770 0.76 RORA (0.47) HTR2ACTSVCTSLMAPT
SCHEMBL29104758 0.76 RORA (0.47) HTR2ACTSVCTSLMAPT
SCHEMBL22288362 0.76 CYP1A2 (0.51) PTPN1BCHE
SCHEMBL6059665 0.75 CTSV (0.49) DHODHHTR2ACTSVCTSLMAPT
SCHEMBL23527407 0.75 HTR2A (0.48) PTPN1HTR2AL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5091439-A Using arene iron complex as curing agent CIBA-GEIGY CORPORATION (US) 1992-02-25 US claimed
EP-0250364-B1 PROCESS FOR CURING POLYURETHANE LACQUERS CIBA-GEIGY AG (CH) 1991-10-23 EP claimed
EP-0265373-B1 PROCESS FOR CURING POLYISOCYANATE COATINGS CIBA-GEIGY AG (CH) 1991-03-13 EP claimed
US-4861806-A PHOTOPOLYMERIZATION, LATENCY CIBA-GEIGY CORPORATION (US) 1989-08-29 US claimed
EP-0265373-A1 Process for curing polyisocyanate coatings CIBA-GEIGY AG (CH) 1988-04-27 EP claimed
EP-0250364-A2 Process for curing polyurethane lacquers CIBA-GEIGY AG (CH) 1987-12-23 EP claimed
US-5091439-A Using arene iron complex as curing agent CIBA-GEIGY CORPORATION (US) 1992-02-25 US disclosed
EP-0250364-B1 PROCESS FOR CURING POLYURETHANE LACQUERS CIBA-GEIGY AG (CH) 1991-10-23 EP disclosed
US-4861806-A PHOTOPOLYMERIZATION, LATENCY CIBA-GEIGY CORPORATION (US) 1989-08-29 US disclosed
EP-0265373-A1 Process for curing polyisocyanate coatings CIBA-GEIGY AG (CH) 1988-04-27 EP disclosed
EP-0250364-A2 Process for curing polyurethane lacquers CIBA-GEIGY AG (CH) 1987-12-23 EP disclosed