Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690115 | 0.90 | ADRA2A (0.39) | ADRA2APOLBNPC1ALDH1A1RAB9A | |
| SCHEMBL9661541 | 0.83 | POLB (0.38) | ADRA2APOLBNPC1ALDH1A1RAB9A | |
| SCHEMBL9658728 | 0.78 | POLB (0.37) | ADRA2APOLBNPC1ALDH1A1RAB9A | |
| SCHEMBL9660717 | 0.77 | NPC1 (0.44) | NPC1ALDH1A1RAB9ACASP3SENP8 | |
| SCHEMBL9690026 | 0.75 | TSHR (0.38) | NPC1ALDH1A1RAB9ACASP3SENP8 | |
| SCHEMBL9689465 | 0.73 | NOTUM (0.32) | NPC1ALDH1A1RAB9AKMT2ANPSR1 | |
| SCHEMBL9658741 | 0.68 | NPC1 (0.36) | ADRA2APOLBNPC1ALDH1A1RAB9A | |
| SCHEMBL9658738 | 0.68 | NPC1 (0.36) | ADRA2APOLBNPC1ALDH1A1RAB9A | |
| SCHEMBL9690040 | 0.68 | KMT2A (0.43) | ADRA2APOLBNPC1ALDH1A1RAB9A | |
| SCHEMBL9690119 | 0.68 | ADRA2A (0.49) | ADRA2APOLBNPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520274-A2 | 2-(-4-substituted-phenylhydrazino)-2-thiazoline and 2-(-4-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |