Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.31 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.30 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660457 | 0.85 | ALDH1A1 (0.39) | ALDH1A1NPSR1 | |
| SCHEMBL9690703 | 0.84 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2NPSR1POLB | |
| SCHEMBL9658792 | 0.81 | ALDH1A1 (0.44) | ALDH1A1NPSR1TSHR | |
| SCHEMBL9660900 | 0.80 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2NPSR1POLB | |
| SCHEMBL9661599 | 0.80 | ALDH1A1 (0.42) | ALDH1A1LMNANPSR1POLB | |
| SCHEMBL9660717 | 0.78 | NPC1 (0.44) | ALDH1A1NPSR1KIF11TSHR | |
| SCHEMBL9660718 | 0.74 | ALDH1A1 (0.40) | ALDH1A1LMNAHTTKIF11PTPRZ1 | |
| SCHEMBL11747051 | 0.72 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL9661616 | 0.69 | LMNA (0.37) | ALDH1A1LMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL9661614 | 0.69 | LMNA (0.37) | ALDH1A1LMNAMAPK1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520274-A2 | 2-(-4-substituted-phenylhydrazino)-2-thiazoline and 2-(-4-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |