Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9661529 | 0.89 | ALDH1A1 (0.33) | ALDH1A1NPC1RAB9AMAPTATM | |
| SCHEMBL9660407 | 0.86 | ALDH1A1 (0.31) | ALDH1A1MAPTATM | |
| SCHEMBL9660892 | 0.86 | ALDH1A1 (0.31) | ALDH1A1MAPTATM | |
| SCHEMBL9690083 | 0.83 | CETP (0.38) | ALDH1A1NPC1DHFRRAB9AKCNH2 | |
| SCHEMBL9661596 | 0.79 | SMN1; SMN2 (0.39) | ALDH1A1NPC1MEN1TSHRKMT2A | |
| SCHEMBL9660409 | 0.73 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL9660857 | 0.68 | NISCH (0.39) | NISCHALDH1A1NPC1MEN1TSHR | |
| SCHEMBL9660740 | 0.68 | NPC1 (0.41) | NISCHNPC1MEN1TSHRKMT2A | |
| SCHEMBL9660852 | 0.68 | NISCH (0.39) | NISCHALDH1A1NPC1MEN1TSHR | |
| SCHEMBL12282928 | 0.67 | TSHR (0.41) | NISCHALDH1A1TSHRDHFRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520274-A2 | 2-(-4-substituted-phenylhydrazino)-2-thiazoline and 2-(-4-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |