Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 6/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660733 | 0.83 | NISCH (0.39) | KCNH2SCN10AALDH1A1NPC1RAB9A | |
| SCHEMBL9690691 | 0.82 | MAPT (0.46) | KCNH2ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9690093 | 0.76 | ALDH1A1 (0.34) | CETPKCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9581166 | 0.75 | ALDH1A1 (0.39) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9690000 | 0.74 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL9690703 | 0.74 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9689560 | 0.74 | ALDH1A1 (0.36) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9689432 | 0.74 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL11747051 | 0.73 | ALDH1A1 (0.53) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9690773 | 0.71 | GRIN2D (0.37) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520275-A2 | 2-(3-Substituted phenylhydrazino)-2-thiazoline and 2-(3-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |