Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660750 | 0.84 | ALDH1A1 (0.44) | ALDH1A1NPSR1POLBSMN1; SMN2LMNA | |
| SCHEMBL9690768 | 0.83 | ALDH1A1 (0.50) | ALDH1A1NPSR1MAPTSMN1; SMN2GAA | |
| SCHEMBL9660900 | 0.78 | ALDH1A1 (0.42) | ALDH1A1NPSR1POLBEPAS1SMN1; SMN2 | |
| SCHEMBL9661599 | 0.78 | ALDH1A1 (0.42) | ALDH1A1NPSR1POLBLMNA | |
| SCHEMBL9690026 | 0.78 | TSHR (0.38) | ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9690716 | 0.76 | ALDH1A1 (0.39) | ALDH1A1NPSR1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9690093 | 0.74 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9660457 | 0.73 | ALDH1A1 (0.39) | ALDH1A1NPSR1 | |
| SCHEMBL9690700 | 0.73 | ALDH1A1 (0.39) | ALDH1A1NPSR1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9581166 | 0.73 | ALDH1A1 (0.39) | ALDH1A1NPSR1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520275-A2 | 2-(3-Substituted phenylhydrazino)-2-thiazoline and 2-(3-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |