Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660787 | 1.00 | KMT2A (0.36) | KMT2AMEN1EPAS1ALDH1A1POLB | |
| SCHEMBL9660700 | 0.86 | ALDH1A1 (0.35) | ALDH1A1POLBSMN1; SMN2ESPL1LMNA | |
| SCHEMBL9660705 | 0.86 | ALDH1A1 (0.35) | ALDH1A1POLBSMN1; SMN2ESPL1LMNA | |
| SCHEMBL9660882 | 0.84 | KMT2A (0.32) | KMT2AMEN1EPAS1 | |
| SCHEMBL9660879 | 0.84 | KMT2A (0.32) | KMT2AMEN1EPAS1 | |
| SCHEMBL9661616 | 0.80 | LMNA (0.37) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9661614 | 0.80 | LMNA (0.37) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9658738 | 0.79 | NPC1 (0.36) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9658741 | 0.79 | NPC1 (0.36) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9690033 | 0.78 | SMN1; SMN2 (0.39) | KMT2AMEN1EPAS1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520274-A2 | 2-(-4-substituted-phenylhydrazino)-2-thiazoline and 2-(-4-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |