Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9661605 | 0.86 | KMT2A (0.38) | KMT2AMEN1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL9660754 | 0.80 | KIF11 (0.41) | KMT2AMEN1CA2HPGDNPC1 | |
| SCHEMBL9660927 | 0.79 | NPC1 (0.48) | KMT2AMEN1HPGDNPC1RAB9A | |
| SCHEMBL9690711 | 0.78 | POLB (0.41) | KMT2AMEN1CA2HPGDNPC1 | |
| SCHEMBL9660727 | 0.74 | KMT2A (0.39) | KMT2AMEN1HPGDNPC1RAB9A | |
| SCHEMBL9660140 | 0.74 | NPY1R (0.39) | KMT2AMEN1NPC1GAA | |
| SCHEMBL9660900 | 0.71 | ALDH1A1 (0.42) | KMT2AMEN1CA2RAB9ASMN1; SMN2 | |
| SCHEMBL9660462 | 0.71 | HPGD (0.39) | KMT2AMEN1HPGDNPC1RAB9A | |
| SCHEMBL9660795 | 0.71 | KMT2A (0.36) | KMT2AMEN1SMN1; SMN2EPAS1ALDH1A1 | |
| SCHEMBL9660787 | 0.71 | KMT2A (0.36) | KMT2AMEN1SMN1; SMN2EPAS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520274-A2 | 2-(-4-substituted-phenylhydrazino)-2-thiazoline and 2-(-4-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |