Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660851 | 1.00 | SCN5A (0.38) | SCN5AMAPTALDH1A1ATMNPC1 | |
| SCHEMBL9660857 | 0.82 | NISCH (0.39) | SCN5AMAPTALDH1A1ATMNPC1 | |
| SCHEMBL9660852 | 0.82 | NISCH (0.39) | SCN5AMAPTALDH1A1ATMNPC1 | |
| SCHEMBL9661581 | 0.80 | NPC1 (0.44) | MAPTALDH1A1ATMNPC1RAB9A | |
| SCHEMBL9661588 | 0.80 | NPC1 (0.44) | MAPTALDH1A1ATMNPC1RAB9A | |
| SCHEMBL9660834 | 0.73 | LMNA (0.36) | ALDH1A1LMNA | |
| SCHEMBL9661614 | 0.71 | LMNA (0.37) | MAPTALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL10841304 | 0.71 | ALDH1A1 (0.46) | MAPTALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL10841300 | 0.71 | ALDH1A1 (0.46) | MAPTALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL9690058 | 0.70 | MAPT (0.34) | MAPTALDH1A1ATMRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520274-A2 | 2-(-4-substituted-phenylhydrazino)-2-thiazoline and 2-(-4-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |