SCHEMBL9664358

SCHEMBL9664358

NC(=O)CN1C=CC(=S)CC1=O

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
APEX1 P27695 1/20 0.34
BLM P54132 1/20 0.34
RAB9A P51151 1/20 0.33
SIGMAR1 Q99720 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10662380 0.86
SCHEMBL9332302 0.84 GSK3A (0.39) TSHRAPEX1
SCHEMBL9665293 0.81 MMP1 (0.32)
SCHEMBL9522908 0.74 ALDH1A1 (0.32) BLMRAB9A
SCHEMBL9664387 0.71
SCHEMBL9820567 0.70
SCHEMBL9664837 0.70
SCHEMBL7465920 0.67
SCHEMBL9354170 0.63
SCHEMBL10660004 0.62 NPC1 (0.35) RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0209751-B1 CEPHALOSPORIN DERIVATIVES AND BACTERICIDES CONTAINING THE SAME MEIJI SEIKA KAISHA LTD. (JP) 1992-09-16 EP disclosed
US-4758557-A Cephalosporin derivatives and bactericides containing the same MEIJI SEIKA KAISHA, LTD. (JP) 1988-07-19 US disclosed
EP-0209751-A2 Cephalosporin derivatives and bactericides containing the same MEIJI SEIKA KAISHA LTD. (JP) 1987-01-28 EP disclosed