Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 6/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 4/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 2/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8955009 | 0.88 | HTT (0.52) | ALDH1A1HTTF2PRSS1KAT6A | |
| SCHEMBL8954993 | 0.85 | CASR (0.41) | ALDH1A1DPP7F2PRSS1KAT6A | |
| Bicarbonate SCHEMBL9665131 | 0.81 | F10 (0.57) | F2PRSS1F10PLGPLAU | |
| SCHEMBL8954682 | 0.80 | ALOX5AP (0.38) | ALDH1A1DPP7F2PRSS1KAT6A | |
| SCHEMBL8954843 | 0.79 | MMP8 (0.38) | ALDH1A1KAT6AF10CASR | |
| SCHEMBL8954607 | 0.79 | CASR (0.36) | DPP7KAT6AF10CASR | |
| SCHEMBL9665755 | 0.79 | CASR (0.38) | DPP7F2PRSS1KAT6AF10 | |
| SCHEMBL8954708 | 0.78 | CASR (0.39) | DPP7F2PRSS1KAT6AF10 | |
| SCHEMBL9665029 | 0.77 | CASR (0.41) | DPP7F2PRSS1KAT6AF10 | |
| SCHEMBL8954772 | 0.76 | F10 (0.40) | F2KAT6AF10PLAUCASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511347-A1 | META-SUBSTITUTED PHENYL ALANINE DERIVATIVES | Pentapharm A.G. (CH) | 1992-11-04 | — | — | EP | disclosed |