Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | HRH2 | P25021 | 3/20 | 0.67 |
| ▸ | HRH1 | P35367 | 3/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | THRA | P10827 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14054622 | 0.89 | KDM4E (0.69) | KDM4EHRH2HRH1HRH3L3MBTL1 | |
| SCHEMBL6981478 | 0.86 | KDM4E (0.89) | KDM4EHRH2HRH1HRH3L3MBTL1 | |
| SCHEMBL5213285 | 0.86 | KDM4E (0.89) | KDM4EHRH2HRH1HRH3L3MBTL1 | |
| SCHEMBL491803 | 0.85 | KDM4E (0.92) | KDM4EHRH2HRH1HRH3THRB | |
| SCHEMBL5855860 | 0.83 | KDM4E (0.90) | KDM4EHRH2HRH1HRH3THRB | |
| SCHEMBL9530115 | 0.82 | ALDH1A1 (0.81) | KDM4EHRH2HRH1HRH3THRA | |
| SCHEMBL7250762 | 0.82 | KDM4E (0.70) | KDM4EHRH2HRH1HRH3L3MBTL1 | |
| SCHEMBL10818222 | 0.82 | HRH2 (0.75) | HRH2HRH1HRH3THRATHRB | |
| SCHEMBL13246598 | 0.81 | RAB9A (0.61) | KDM4EHRH2HRH1HRH3DRD2 | |
| SCHEMBL13305526 | 0.81 | KDM4E (0.76) | KDM4EHRH2HRH1HRH3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324472-B1 | KETENEDITHIOACETAL DERIVATIVES AND PROCESSES FOR PRODUCING THE SAME AS WELL AS A COMPOSITION CONTAINING THE SAME | NIHON NOHYAKU CO., LTD. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-5098928-A | Antilipemic agents and treatment of arteriosclerosis | NIHON NOHYAKU CO., LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0324472-A2 | Ketenedithioacetal derivatives and processes for producing the same as well as a composition containing the same | NIHON NOHYAKU CO., LTD. (JP) | 1989-07-19 | — | — | EP | disclosed |