Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 1/20 | 0.46 |
| ▸ | NMT1 | P30419 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1475977 | 0.98 | NMT2 (0.46) | NMT2NMT1F10SMN1; SMN2SLC6A4 | |
| SCHEMBL9664669 | 0.88 | GAA (0.47) | SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8499762 | 0.84 | TACR1 (0.51) | NMT2NMT1F10SLC6A4TACR1 | |
| SCHEMBL31693930 | 0.84 | DPP4 (0.44) | F10SMN1; SMN2ALDH1A1 | |
| SCHEMBL31202616 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL4189434 | 0.83 | LMNA (0.50) | POLB | |
| SCHEMBL32667549 | 0.83 | MEN1 (0.57) | SMN1; SMN2SLC6A4SLC6A2ALDH1A1POLB | |
| SCHEMBL1477277 | 0.83 | GBA1 (0.50) | ALDH1A1 | |
| SCHEMBL6469067 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL8500162 | 0.83 | TACR1 (0.50) | F10SLC6A4TACR1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784401-A4 | UREA DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD (CA) | 2009-07-15 | — | — | EP | disclosed |
| EP-1784401-A1 | UREA DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | Neuromed Pharmaceuticals, Ltd. (CA) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006024160-A1 | UREA DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD. (CA) | 2006-03-09 | — | — | WO | disclosed |
| US-5116846-A | N-ARALKYL PIPERIDINE DERIVATIVES AS PSYCHOTROPIC DRUGS | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0449186-A2 | N-aralkyl piperidine derivatives as psychotropic drugs | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-10-02 | — | — | EP | disclosed |