Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544609 | 0.92 | TSHR (0.38) | HSD17B10PDE4BPDE7A | |
| SCHEMBL7308635 | 0.83 | — | — | |
| SCHEMBL9429570 | 0.80 | ALDH1A1 (0.38) | MMEAGTR1 | |
| SCHEMBL9663223 | 0.79 | AGTR1 (0.30) | AGTR1 | |
| SCHEMBL9309399 | 0.79 | TSHR (0.34) | AGTR1 | |
| SCHEMBL7310871 | 0.79 | AGTR2 (0.37) | AGTR1 | |
| SCHEMBL9311003 | 0.78 | AGTR1 (0.35) | AGTR1 | |
| SCHEMBL9663265 | 0.78 | GRM2 (0.32) | — | |
| SCHEMBL9429517 | 0.76 | ALDH1A1 (0.36) | — | |
| SCHEMBL9664761 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514198-A1 | 1H-Imidazol-1-yl-methyl benzofuran derivatives with the imidazolyl moiety being substituted by a cycloalkyl group | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |