Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96332 | 0.76 | ALDH1A1 (0.38) | NPC1POLBRAB9AKMT2AALDH1A1 | |
| SCHEMBL97250 | 0.75 | BRD4 (0.48) | POLBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5297293 | 0.74 | BRD4 (0.47) | POLBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5297286 | 0.74 | BRD4 (0.46) | POLBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL98450 | 0.73 | ALDH1A1 (0.37) | NPC1POLBRAB9AKMT2AATM | |
| SCHEMBL5289604 | 0.70 | BRD4 (0.43) | NPC1POLBRAB9APDE4APDE4B | |
| SCHEMBL98006 | 0.67 | PARP1 (0.32) | NPC1POLBRAB9AKMT2AALDH1A1 | |
| SCHEMBL98191 | 0.65 | MTNR1A (0.34) | KMT2AATMALDH1A1MTNR1AMTNR1B | |
| SCHEMBL19337380 | 0.62 | ALDH1A1 (0.46) | NPC1POLBRAB9AKMT2AALDH1A1 | |
| SCHEMBL12035686 | 0.62 | ALDH1A1 (0.46) | NPC1POLBRAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426128-A1 | Carbostyril compound | Otsuka Pharmaceutical Co., Limited (JP) | 2012-03-07 | — | — | EP | disclosed |