Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17993501 | 0.80 | HTT (0.65) | HTTSMN1; SMN2NPC1MAPK8LMNA | |
| SCHEMBL4162497 | 0.80 | HTT (0.65) | HTTSMN1; SMN2NPC1MAPK8LMNA | |
| SCHEMBL17866854 | 0.80 | MEN1 (0.52) | MAPK8LMNAEPHX2KMT2AALDH1A1 | |
| SCHEMBL9665038 | 0.80 | MEN1 (0.52) | MAPK8LMNAEPHX2KMT2AALDH1A1 | |
| SCHEMBL7905681 | 0.78 | HTT (0.71) | HTTSMN1; SMN2NPC1LMNATDP1 | |
| SCHEMBL4928502 | 0.76 | HTT (0.73) | HTTSMN1; SMN2NPC1MAPK8LMNA | |
| SCHEMBL2494898 | 0.76 | HTT (0.73) | HTTSMN1; SMN2NPC1MAPK8LMNA | |
| SCHEMBL9667193 | 0.75 | KMT2A (0.51) | HTTSMN1; SMN2MAPK8KMT2AALDH1A1 | |
| SCHEMBL14678385 | 0.75 | DDAH1 (0.68) | HTTSMN1; SMN2NPC1LMNAKMT2A | |
| SCHEMBL3369060 | 0.74 | HTT (0.76) | HTTSMN1; SMN2NPC1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481289-A1 | N-Fumaramide acid derivatives and fungicides containing them | BASF Aktiengesellschaft (DE) | 1992-04-22 | — | — | EP | disclosed |