Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.78 |
| ▸ | GAA | P10253 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.66 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL392680 | 0.88 | ALDH1A1 (1.00) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL30216480 | 0.88 | ALDH1A1 (1.00) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL4861809 | 0.88 | ALDH1A1 (1.00) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL478614 | 0.88 | ALDH1A1 (1.00) | ALDH1A1GAAKMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL7840775 | 0.86 | ALDH1A1 (0.97) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL10898781 | 0.82 | KDM4E (0.57) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL11539697 | 0.81 | KDM4E (0.60) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL8825117 | 0.80 | KMT2A (0.79) | ALDH1A1GAAKMT2AMEN1POLB | |
| SCHEMBL25583428 | 0.80 | KDM4E (0.76) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL25583427 | 0.80 | KDM4E (0.58) | ALDH1A1GAAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184550-B1 | 5-AMINO-4-HYDROXY VALERYL AMIDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-03-18 | — | — | EP | disclosed |
| US-4931591-A | Novel 5-amino-4-hydroxyvaleryl derivatives | CIBA-GEIGY CORPORATION (US) | 1990-06-05 | — | — | US | disclosed |
| US-4727060-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| EP-0184550-A2 | 5-Amino-4-hydroxy valeryl amide derivatives | CIBA-GEIGY AG (CH) | 1986-06-11 | — | — | EP | disclosed |