Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | PPARA | Q07869 | 5/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10389915 | 1.00 | ALDH1A1 (0.47) | ALDH1A1PRKCAPRKCDSRRPPARG | |
| SCHEMBL7326900 | 0.84 | SRR (0.57) | SRRPPARGPPARA | |
| SCHEMBL9665676 | 0.84 | SRR (0.57) | SRRPPARGPPARA | |
| SCHEMBL22035801 | 0.80 | ALDH1A1 (0.61) | ALDH1A1SRRPPARGPPARACTRB1 | |
| SCHEMBL9555203 | 0.79 | CTSB (0.48) | ALDH1A1SRRPPARGPPARACTRB1 | |
| SCHEMBL522510 | 0.79 | ALDH1A1 (0.62) | ALDH1A1PRKCAPRKCDMAPK1L3MBTL1 | |
| SCHEMBL19456196 | 0.78 | ALDH1A1 (0.52) | ALDH1A1SRRPPARGPPARACTRB1 | |
| SCHEMBL19456194 | 0.78 | ALDH1A1 (0.52) | ALDH1A1SRRPPARGPPARACTRB1 | |
| SCHEMBL10509970 | 0.78 | KLK7 (0.48) | ALDH1A1SRRPPARGPPARACTRB1 | |
| SCHEMBL28246707 | 0.77 | ALDH1A1 (0.60) | ALDH1A1PRKCAPRKCDMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184550-B1 | 5-AMINO-4-HYDROXY VALERYL AMIDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-03-18 | — | — | EP | disclosed |
| US-4931591-A | Novel 5-amino-4-hydroxyvaleryl derivatives | CIBA-GEIGY CORPORATION (US) | 1990-06-05 | — | — | US | disclosed |
| US-4727060-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| EP-0184550-A2 | 5-Amino-4-hydroxy valeryl amide derivatives | CIBA-GEIGY AG (CH) | 1986-06-11 | — | — | EP | disclosed |