Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRR | Q9GZT4 | 2/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 16/20 | 0.53 |
| ▸ | PPARA | Q07869 | 13/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9665676 | 1.00 | SRR (0.57) | SRRACEPPARGPPARA | |
| SCHEMBL10389915 | 0.84 | ALDH1A1 (0.47) | SRRPPARGPPARA | |
| SCHEMBL9665207 | 0.84 | ALDH1A1 (0.47) | SRRPPARGPPARA | |
| SCHEMBL27486488 | 0.82 | SRR (0.56) | SRRACEPPARGPPARA | |
| SCHEMBL1486323 | 0.81 | SRR (0.62) | SRRACEPPARGPPARA | |
| SCHEMBL2626716 | 0.81 | SRR (0.62) | SRRACEPPARGPPARA | |
| SCHEMBL1486321 | 0.81 | SRR (0.62) | SRRACEPPARGPPARA | |
| SCHEMBL9554844 | 0.81 | ACE (0.61) | SRRACEPPARGPPARA | |
| SCHEMBL28216110 | 0.79 | SRR (0.61) | SRRACEPPARGPPARA | |
| SCHEMBL28216109 | 0.79 | SRR (0.61) | SRRACEPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184550-B1 | 5-AMINO-4-HYDROXY VALERYL AMIDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-03-18 | — | — | EP | disclosed |
| EP-0396065-A1 | Novel amino acid derivatives possessing renin-inhibitory activities | Japan Tobacco Inc. (JP) | 1990-11-07 | — | — | EP | disclosed |
| US-4931591-A | Novel 5-amino-4-hydroxyvaleryl derivatives | CIBA-GEIGY CORPORATION (US) | 1990-06-05 | — | — | US | disclosed |
| US-4727060-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| EP-0184550-A2 | 5-Amino-4-hydroxy valeryl amide derivatives | CIBA-GEIGY AG (CH) | 1986-06-11 | — | — | EP | disclosed |