Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTPA | P49638 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9666395 | 0.81 | KMT2A (0.47) | KMT2A | |
| SCHEMBL9666239 | 0.79 | IDO1 (0.33) | MEN1KMT2AALOX5 | |
| SCHEMBL3595127 | 0.76 | IDO1 (0.32) | — | |
| SCHEMBL2947678 | 0.74 | KDM4E (0.39) | MEN1KMT2A | |
| SCHEMBL8716319 | 0.73 | NPSR1 (0.36) | — | |
| SCHEMBL8537504 | 0.73 | TTPA (0.37) | TTPAMEN1KMT2APDE4APDE3A | |
| SCHEMBL2911639 | 0.72 | ADCY1 (0.42) | MEN1KMT2A | |
| SCHEMBL9285775 | 0.72 | TTPA (0.36) | TTPAMEN1KMT2APDE4APDE3A | |
| SCHEMBL8534827 | 0.72 | TTPA (0.39) | TTPAMEN1KMT2APDE4APDE3A | |
| SCHEMBL2905508 | 0.71 | LMNA (0.44) | MEN1KMT2AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273647-B1 | COUMARAN DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-03-11 | — | — | EP | disclosed |
| US-4857516-A | Coumaran derivatives and their pharmaceutical use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0273647-A1 | Coumaran derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-07-06 | — | — | EP | disclosed |