Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790237 | 0.83 | NPC1 (0.44) | NPC1RAB9AALDH1A1MAPTMAPK1 | |
| SCHEMBL10918956 | 0.82 | NPC1 (0.44) | NPC1RAB9AALDH1A1MAPTMAPK1 | |
| SCHEMBL10918952 | 0.82 | NPC1 (0.44) | NPC1RAB9AALDH1A1MAPTMAPK1 | |
| SCHEMBL10516600 | 0.79 | NPC1 (0.41) | NPC1RAB9AALDH1A1MAPTMAPK1 | |
| SCHEMBL2554286 | 0.79 | ALDH1A1 (0.43) | NPC1RAB9AALDH1A1MAPTMAPK1 | |
| SCHEMBL7648727 | 0.79 | MAOA (0.39) | NPC1RAB9AALDH1A1MAPTACHE | |
| SCHEMBL18379890 | 0.79 | RAB9A (0.41) | NPC1RAB9AALDH1A1MAPTMAPK1 | |
| SCHEMBL1454008 | 0.78 | ALDH1A1 (0.52) | NPC1RAB9AALDH1A1MAPTMAPK1 | |
| SCHEMBL19798033 | 0.74 | NPC1 (0.48) | NPC1RAB9AALDH1A1MAPTACHE | |
| SCHEMBL5168911 | 0.74 | NPC1 (0.65) | NPC1RAB9AALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5090994-A | HETEROCYCLIC COMPOUNDS AND HERBICIDAL COMPOSITIONS CONTAINING THE COMPOUNDS AS EFFECTIVE COMPONENTS | AGRO-KANESHO CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |
| EP-0384973-A2 | Heterocyclic compounds, method for preparing the same and herbicidal compositions containing the compounds as effective components | AGRO-KANESHO CO., LTD. (JP) | 1990-09-05 | — | — | EP | disclosed |