Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710558 | 0.92 | MMP8 (0.38) | MMP8MMP3KDM4ETBXA2RMAPT | |
| SCHEMBL9710706 | 0.86 | OPRM1 (0.36) | MMP8MMP3KDM4EALDH1A1MCL1 | |
| SCHEMBL8954944 | 0.84 | CASR (0.38) | MMP8MMP3KAT6AOPRM1CASR | |
| SCHEMBL8954799 | 0.83 | F10 (0.48) | — | |
| SCHEMBL9665510 | 0.81 | F10 (0.38) | — | |
| SCHEMBL8954843 | 0.80 | MMP8 (0.38) | MMP8MMP3KDM4EALDH1A1MCL1 | |
| SCHEMBL9710123 | 0.78 | F10 (0.37) | ALDH1A1TBXA2RKAT6APOLB | |
| SCHEMBL9710711 | 0.74 | KMT2A (0.40) | KDM4EALDH1A1LMNAPOLBHTT | |
| SCHEMBL9665755 | 0.72 | CASR (0.38) | KAT6ADPP4CASR | |
| SCHEMBL8954996 | 0.71 | F10 (0.39) | MMP8MMP3NR1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016549-A1 | PARASUBSTITUTED PHENYLALANINE DERIVATES | PENTAPHARM AG (CH) | 1992-10-01 | — | — | WO | disclosed |