Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD5 | P21918 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HCN4 | Q9Y3Q4 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9667804 | 0.99 | GAA (0.41) | GAASMN1; SMN2DRD1DRD4DRD5 | |
| SCHEMBL9667529 | 0.94 | GAA (0.41) | GAASMN1; SMN2DRD1DRD4DRD5 | |
| SCHEMBL9667729 | 0.88 | GAA (0.38) | GAASMN1; SMN2DRD1DRD4DRD5 | |
| SCHEMBL9667385 | 0.87 | ALOX5 (0.38) | DRD1DRD4DRD5TSHRDRD3 | |
| SCHEMBL9667498 | 0.85 | GAA (0.40) | GAASMN1; SMN2DRD1DRD4DRD5 | |
| SCHEMBL9667637 | 0.85 | GAA (0.38) | GAASMN1; SMN2DRD1DRD4DRD5 | |
| SCHEMBL9667687 | 0.85 | HCN4 (0.34) | GAASMN1; SMN2DRD1DRD4DRD5 | |
| Hydrochloric Acid SCHEMBL9667430 | 0.84 | GAA (0.39) | GAASMN1; SMN2DRD1DRD4DRD5 | |
| Hydrochloric Acid SCHEMBL9666414 | 0.84 | GAA (0.38) | GAASMN1; SMN2DRD1DRD4DRD5 | |
| SCHEMBL9667686 | 0.83 | PTGS2 (0.39) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259793-B1 | NAPHTHYL DERIVATIVES, MEDICAMENTS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | Dr. Karl Thomae GmbH (DE) | 1992-07-01 | — | — | EP | disclosed |
| US-4871735-A | HYPOTENSIVE, ANTIISCHEMIC AGENTS | DR. KARL THOMAE GMBH | 1989-10-03 | — | — | US | disclosed |
| EP-0259793-A1 | Naphthyl derivatives, medicaments containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-03-16 | — | — | EP | disclosed |