Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4655851 | 0.83 | LMNA (0.44) | ALDH1A1STAT3PKMCYP24A1LMNA | |
| SCHEMBL7840144 | 0.82 | ALDH1A1 (0.43) | ALDH1A1STAT3PKMCYP24A1LMNA | |
| SCHEMBL6005431 | 0.82 | PKM (0.43) | ALDH1A1STAT3PKMCYP24A1LMNA | |
| SCHEMBL18092987 | 0.81 | ALDH1A1 (0.45) | ALDH1A1STAT3PKMCYP24A1LMNA | |
| SCHEMBL18092988 | 0.81 | ALDH1A1 (0.45) | ALDH1A1STAT3PKMCYP24A1LMNA | |
| SCHEMBL1463518 | 0.80 | PKM (0.51) | ALDH1A1STAT3PKMCYP24A1LMNA | |
| SCHEMBL1463520 | 0.80 | PKM (0.51) | ALDH1A1STAT3PKMCYP24A1LMNA | |
| SCHEMBL1464675 | 0.80 | PKM (0.51) | ALDH1A1STAT3PKMCYP24A1LMNA | |
| SCHEMBL6007086 | 0.77 | PARL (0.40) | ALDH1A1STAT3PKMCYP24A1LMNA | |
| SCHEMBL12936205 | 0.77 | CA12 (0.41) | ALDH1A1STAT3LMNAVDRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5157038-A | Antidepressants; tranquilizers; treatment of schizophrenia and epilepsy; antilepmic agents | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1992-10-20 | — | — | US | disclosed |