Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6338495 | 0.79 | KMT2A (0.56) | PTGS2SMN1; SMN2KMT2A | |
| SCHEMBL8167493 | 0.77 | GSK3B (0.54) | — | |
| SCHEMBL31471473 | 0.75 | ACHE (0.69) | ALDH1A1HPGDMAPK1ACHERAB9A | |
| SCHEMBL29373699 | 0.75 | ACHE (0.69) | ALDH1A1HPGDMAPK1ACHERAB9A | |
| SCHEMBL301247 | 0.75 | ACHE (0.69) | ALDH1A1HPGDMAPK1ACHERAB9A | |
| SCHEMBL1471565 | 0.75 | MAPT (0.46) | MAPTALDH1A1HPGDTP53CYP3A4 | |
| SCHEMBL10980169 | 0.75 | PTGS2 (0.53) | HPGDMAOBHSD17B10TDP1NOTUM | |
| SCHEMBL19577801 | 0.73 | ACHE (0.65) | ALDH1A1HPGDMAPK1ACHERAB9A | |
| SCHEMBL18797759 | 0.73 | ACHE (0.65) | ALDH1A1HPGDMAPK1ACHERAB9A | |
| SCHEMBL3729848 | 0.72 | CAMK2D (0.44) | NOTUMACHEPTGS2L3MBTL1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098991-A | Process of preparing polyamide-imide and polyimide polymers from acid anhydrides and dianhydrides of disubstituted maleic anhydrides | AMOCO CORPORATION (US) | 1992-03-24 | — | — | US | disclosed |
| US-5003085-A | Acid anhydrides and dianhydrides of disubstituted maleic anhydrides | AMOCO CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |