Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.77 |
| ▸ | NPC1 | O15118 | 3/20 | 0.77 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.72 |
| ▸ | TUBB | P07437 | 1/20 | 0.72 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.72 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.72 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.72 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.72 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.72 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.72 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.72 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.72 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.72 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.72 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.72 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.72 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 8/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668297 | 1.00 | RAB9A (0.77) | RAB9ANPC1TUBB4ATUBBTUBA3C | |
| SCHEMBL9669704 | 0.96 | RAB9A (0.71) | RAB9ANPC1TUBB4ATUBBTUBA3C | |
| SCHEMBL28471139 | 0.87 | RAB9A (1.00) | RAB9ANPC1TUBB4ATUBBTUBA3C | |
| SCHEMBL8257172 | 0.87 | MAPT (0.74) | RAB9ANPC1TUBB4ATUBBTUBA3C | |
| SCHEMBL22925016 | 0.84 | ALDH1A1 (1.00) | RAB9ANPC1TUBB4ATUBBTUBA3C | |
| SCHEMBL13381082 | 0.84 | MEN1 (0.70) | RAB9ANPC1TUBB4ATUBBTUBA3C | |
| SCHEMBL6026750 | 0.83 | MAPT (0.69) | RAB9ANPC1TUBB4ATUBBTUBA3C | |
| SCHEMBL6026757 | 0.83 | MAPT (0.69) | RAB9ANPC1TUBB4ATUBBTUBA3C | |
| SCHEMBL9669033 | 0.83 | SMN1; SMN2 (0.70) | RAB9ANPC1TUBB4ATUBBTUBA3C | |
| SCHEMBL9669673 | 0.83 | PTGS2 (0.71) | RAB9ANPC1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299973-B1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1992-06-17 | — | — | EP | claimed |
| EP-0299973-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS. | UPJOHN CO (US) | 1989-01-25 | — | — | EP | claimed |
| WO-1987006133-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-10-22 | — | — | WO | claimed |
| EP-0299973-B1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0299973-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS. | UPJOHN CO (US) | 1989-01-25 | — | — | EP | disclosed |
| WO-1987006133-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-10-22 | — | — | WO | disclosed |