Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 11/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 9/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.66 |
| ▸ | TUBB | P07437 | 1/20 | 0.66 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.66 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.66 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.66 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.66 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.66 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.66 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.66 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.66 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25605905 | 0.86 | MEN1 (0.69) | PTGS2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13381082 | 0.84 | MEN1 (0.70) | PTGS2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27131245 | 0.83 | PTGS2 (1.00) | PTGS2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL24629107 | 0.83 | PTGS2 (1.00) | PTGS2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9668293 | 0.83 | RAB9A (0.77) | PTGS2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9668297 | 0.83 | RAB9A (0.77) | PTGS2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22925016 | 0.82 | ALDH1A1 (1.00) | PTGS2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL25605398 | 0.82 | MEN1 (0.64) | PTGS2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8257172 | 0.82 | MAPT (0.74) | PTGS2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9669033 | 0.81 | SMN1; SMN2 (0.70) | PTGS2ALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299973-B1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1992-06-17 | — | — | EP | claimed |