Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10560426 | 0.85 | FAAH (0.52) | NPC1RAB9ASMN1; SMN2FAAHPKM | |
| SCHEMBL9670317 | 0.85 | ROCK2 (0.49) | NPC1RAB9AKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9669179 | 0.84 | NPC1 (0.47) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9669188 | 0.84 | PIN1 (0.56) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9669468 | 0.83 | NPC1 (0.54) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL10561560 | 0.82 | FAAH (0.52) | NPC1RAB9ASMN1; SMN2FAAHPKM | |
| SCHEMBL9669437 | 0.81 | RAB9A (0.59) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9669651 | 0.81 | RAB9A (0.58) | NPC1RAB9AKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL28357603 | 0.81 | SMN1; SMN2 (0.60) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9671465 | 0.80 | NPC1 (0.60) | NPC1RAB9AKMT2ASMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63146871-A | — | — | None | — | — | JP | disclosed |
| EP-0254322-B1 | BENZIMIDAZOLE DERIVATIVES | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-09-23 | — | — | EP | disclosed |
| US-4886803-A | CARDIOTONIC AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| JP-S63146871-A | BENZIMIDAZOLE DERIVATIVE | NISSHIN FLOUR MILLING CO LTD | 1988-06-18 | — | — | JP | disclosed |
| EP-0254322-A1 | Benzimidazole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1988-01-27 | — | — | EP | disclosed |