Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.81 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.81 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.81 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.81 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.81 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.81 |
| ▸ | DRD1 | P21728 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902336 | 1.00 | ADRA2A (0.81) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Bromide SCHEMBL7508700 | 0.98 | ADRA2A (0.78) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL8816707 | 0.85 | ADRA2A (0.58) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL9549176 | 0.85 | ADRA2A (0.58) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL8411065 | 0.77 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL15824544 | 0.76 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL15839876 | 0.75 | KDM4C (0.46) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL21091917 | 0.74 | ADRB2 (0.49) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL21091959 | 0.74 | ADRB2 (0.49) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL8904492 | 0.74 | ADRA2A (0.57) | ADRA2AADRA2BADRA2CADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474767-A4 | DOPAMINE AGONISTS | — | 1992-07-08 | — | — | EP | disclosed |
| EP-0474767-A1 | DOPAMINE AGONISTS. | ABBOTT LAB (US) | 1992-03-18 | — | — | EP | disclosed |
| WO-1990015056-A1 | DOPAMINE AGONISTS | ABBOTT LABORATORIES (US) | 1990-12-13 | — | — | WO | disclosed |