Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670156 | 0.96 | BCHE (0.48) | BCHEACHECHRM2CHRM4CHRM1 | |
| SCHEMBL9669494 | 0.92 | BCHE (0.43) | BCHEACHECHRM2CHRM4CHRM1 | |
| SCHEMBL9669370 | 0.84 | BCHE (0.47) | BCHEACHECHRM2ALDH1A1MAPT | |
| SCHEMBL9669489 | 0.81 | BCHE (0.59) | BCHEACHECHRM2CHRM1ALDH1A1 | |
| SCHEMBL9669472 | 0.80 | CHEK1 (0.41) | BCHEACHEALDH1A1APAF1NPC1 | |
| SCHEMBL10481169 | 0.76 | BCHE (0.40) | BCHEACHEALDH1A1HPGDALOX12 | |
| SCHEMBL10481158 | 0.73 | BCHE (0.36) | BCHEACHECHRM2CHRM1ALDH1A1 | |
| SCHEMBL10338752 | 0.71 | KDM4E (0.57) | BCHEACHEALDH1A1MAPTKDM4E | |
| SCHEMBL9595444 | 0.68 | TSPO (0.59) | BCHEACHECHRM2CHRM4CHRM1 | |
| SCHEMBL3259666 | 0.68 | BCHE (0.89) | BCHEACHEALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273401-B1 | ISOINDOLIN-1-ONE DERIVATIVE AND ANTIARRHYTHMIC AGENT | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1992-11-11 | — | — | EP | disclosed |
| US-4849441-A | Isoindolin-1-one derivative and antiarrhythmic agent | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-07-18 | — | — | US | disclosed |
| EP-0273401-A1 | Isoindolin-1-one derivative and antiarrhythmic agent | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1988-07-06 | — | — | EP | disclosed |