Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | HTT | P42858 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9669632 | 0.77 | MAPT (1.00) | MAPTALDH1A1HTTLMNAKDM4E | |
| SCHEMBL422634 | 0.75 | KDM4E (0.63) | MAPTALDH1A1HTTLMNAKDM4E | |
| SCHEMBL5367724 | 0.75 | KDM4E (0.63) | MAPTALDH1A1HTTLMNAKDM4E | |
| SCHEMBL10201244 | 0.74 | ALDH1A1 (0.62) | MAPTALDH1A1HTTLMNAKDM4E | |
| SCHEMBL4575394 | 0.74 | KDM4E (0.58) | MAPTALDH1A1HTTLMNAKDM4E | |
| SCHEMBL18721830 | 0.73 | KDM4E (0.61) | MAPTALDH1A1HTTLMNAKDM4E | |
| SCHEMBL2871452 | 0.73 | KDM4E (0.61) | MAPTALDH1A1HTTLMNAKDM4E | |
| SCHEMBL2871450 | 0.73 | KDM4E (0.61) | MAPTALDH1A1HTTLMNAKDM4E | |
| SCHEMBL9453945 | 0.73 | KDM4E (0.61) | MAPTALDH1A1HTTLMNAKDM4E | |
| SCHEMBL3236045 | 0.73 | KDM4E (1.00) | MAPTALDH1A1HTTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090226500-A1 | SUTURES AND ANTI-SCARRING AGENTS | ANGIOTECH PHARMACEUTICALS, INC (CA) | 2009-09-10 | — | — | US | disclosed |
| EP-0293742-B1 | PROCESS FOR THE PRODUCTION OF 4-NITRO-5-IMIDAZOLYLETHERS AND -THIOETHERS | BASF Aktiengesellschaft (DE) | 1992-07-22 | — | — | EP | disclosed |
| US-4900825-A | REACTING DINITROIMIDAZOLES WITH ALCOHOLS OR MERCAPTANS | BASF AKTIENGSELLSCHAFT (DE) | 1990-02-13 | — | — | US | disclosed |
| EP-0293742-A1 | Process for the production of 4-nitro-5-imidazolylethers and -thioethers | BASF Aktiengesellschaft (DE) | 1988-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090226500-A1 | SUTURES AND ANTI-SCARRING AGENTS | COL1A1, COL2A1, COL14A1 | MAPT 2564/4885ALDH1A1 2866/4885HTT 4120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.